Heat oven to 375°F. Place store bought pie crust in 9-inch glass pie pan and bake as directed on the box.
In large bowl, gently mix apples, cranberries and vanilla. In small bowl, mix remaining filling ingredients.
Add dry ingredients to fruit; toss to coat. Pour into crust-lined pan.
In small bowl, mix all topping ingredients except butter. With pastry blender or fork, cut in butter until crumbly. Sprinkle evenly over filling.
Bake 45 to 55 minutes or until apples are tender, and crust and topping are golden brown. After 15 to 20 minutes of baking, cover crust edge with strips of foil to prevent excessive browning. If desired, serve warm with whipped cream or ice cream.